ELIXIR Core Data Resources feature strongly in first selection of Global Core Biodata Resources

The Global Biodata Coalition has announced the first set of Global Core Biodata Resources (GCBRs). The list comprises 37 resources whose long term funding and sustainability is critical to life science and biomedical research worldwide.  ELIXIR Core Data Resources (CDRs) make up 12 of the 37 resources, showing the impact of European data resources on global scientific research (Table 1).

GCBRs represent key elements within the global life science data infrastructure and their failure would significantly hinder research in the life sciences. The list was drawn up after a rigorous two-stage process by a panel of more than 50 independent experts, building on the selection process used by ELIXIR for its Core Data Resources.

The GBC’s partner funders will now explore suitable funding models to ensure the selected biodata resources have the greatest opportunity of being sustained over the long-term.  ELIXIR supports this process and remains committed to actively promoting and supporting the long term sustainability of fundamental European research data resources. ELIXIR and GBC will also work to further align selection and monitoring processes between the two organisations.

BRENDA Database of enzyme and enzyme-ligand information, across all taxonomic groups, manually extracted from primary literature and extended by text mining procedures, integration of external data and prediction algorithms.
ChEBI Dictionary of molecular entities focused on ‘small’ chemical compounds
ChEMBL Database of bioactive drug-like small molecules, it contains 2-D structures, calculated properties and abstracted bioactivities.
Ensembl Genome browser for vertebrate genomes that supports research in comparative genomics, evolution, sequence variation and transcriptional regulation.
Europe PMC Europe PMC is a repository, providing access to worldwide life sciences articles, books, patents and clinical guidelines.
ENA Nucleotide sequencing information, covering raw sequencing data, sequence assembly information and functional annotation.
InterPro Functional analysis of protein sequences by classifying them into families and predicting the presence of domains and important sites.
Orphadata Science The Orphadata Science platform provides the scientific community with comprehensive, high-quality datasets related to rare diseases and orphan drugs, in a reusable and computable format.
Reactome REACTOME is an open-source, open access, manually curated and peer-reviewed pathway database.
Rhea Rhea is an expert-curated knowledgebase of chemical and transport reactions of biological interest, and the standard for enzyme and transporter annotation in UniProtKB
STRING Known and predicted protein-protein interactions.
UniProt Comprehensive resource for protein sequence and annotation data.
Table 1: ELIXIR CDRs selected as Global Core Biodata Resources

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Fri 16 December 2022