Biodiversity services

Name Description ELIXIR Node

This study is divided into four Work Packages (WP). The first three aim to survey the biodiversity data domain and catalogue and assess relevant research data management elements (WP1), analysis tools, services, and infrastructures (WP2), as well as active and planned projects and stakeholders (WP3).

WP4 aims to grow the ELIXIR Biodiversity Community by collating resources and materials for training and knowledge transfer amongst ELIXIR members and the wider research community.

WP1: Research data management and data interoperability

The aim of WP1 is to survey and catalogue Research Data Management (RDM) elements relevant to the biodiversity domain, with a focus on molecular data but not excluding other relevant data collection activities. By focusing on data management and not data analysis it remains distinct from WP2.

It is aligned with WP3 through the mapping of RDM-related activities being performed as part of ongoing projects (e.g. BGE, BiCIKL, TETTRIs), and will provide some of the substrate for discussions as part of WP3’s planned network event, contributing to creating connections with the wider community (particularly active ELIXIR Nodes).

It will also highlight current capacities and gaps in RDM practices that will feed into WP4’s activities. Development and adoption of best practices in RDM for the biodiversity research domain remain extremely variable, hence the focus here on assessing the current status and collating existing best practices. This will strengthen ELIXIR’s position in the biodiversity domain by leveraging ELIXIR’s RDM-related strengths in other research domains including other ELIXIR Communities.

Lead

Josie Burgin (EMBL-EBI)

Tasks

  • Task 1.1: Collate existing data and metadata standards used to record biodiversity data and metadata, maintaining interoperability beyond genomics (taxonomy, ecological data, traits etc.) including gap identification on FAIRsharing and create or add to an existing Collection.
  • Task 1.2: Develop implementable best practice recommendations for management of biodiversity molecular data in line ongoing projects (e.g. BGE, BiCIKL), connecting this to a dedicated RDMkit domain, at least one hybrid workshop to bring RDMkit to publishable status
  • Task 1.3: Create FAIR Cookbook recipes on recommendations for tools associated with data management (e.g. applications of RO-crate and Ecological Metadata Language-oriented tools).
  • Task 1.4: Build recommendations for recording taxonomic annotation of archived samples and sequences working with NCBI/GBIF/CoL/DiSSCo.
  • Example Case Study: GlobalFungi Database metadata collection and curation to make published data findable and reusable in a research context.

Milestones and deliverables

  • M1.1: List of existing standards and gap analysis in FAIRsharing
  • M1.2: First draft of RDMkit for biodiversity molecular data management
  • M1.3: Linking FAIR Cookbook recipes and RDMkit page/s
  • M1.4: Publish taxonomic recommendations on RDMkit
  • D1.1: Final cross-linked RDMkit and FAIR Cookbook content, standards in FAIRsharing and taxonomic recommendations

WP2: Services, tools, and analysis

The main aims of WP2 are to catalogue, review, and categorise tools, services, and analytical workflows currently in use by ELIXIR Nodes and the wider community, that process and analyse biodiversity-related data, with an emphasis on molecular data. This will include ELIXIR and non-ELIXIR tools.

It remains distinct from WP1 by focusing on data analysis tools, services, and infrastructures and not on data management in research. It will benefit from WP3’s surveys of stakeholders/projects to help identify key tools and services that should be prioritised for review and cataloguing. These priorities can feed into WP4’s training activities by identifying community needs with respect to the usability of important tools and services.

The outputs will ensure that ELIXIR is playing a leading role in identifying and exposing high-quality biodiversity-related analysis tools and services to the wider community of users, as well as fostering the development of such tools and services through connecting ELIXIR Nodes which are active in the domain.

Lead

Toni Gabaldón and Matúš Kalaš

Tasks

  • Task 2.1: Development and population of a curated biodiversity subdomain in Bio.tools, especially for computational tools and workflows applicable to biodiversity research, particularly biodiversity genomics and biodiversity informatics
  • Task 2.2: Review biodiversity-related workflows available in Galaxy and WorkflowHub, a curation effort to maintain a list of biodiversity-relevant workflows, working with Galaxy, the EuroScienceGateway EOSC project, and others, to support the inclusion of key tools
  • Task 2.3: Collate community-wide usage of pipelines for biodiversity data analyses including tools to visualise and promote the data and publish the tools and workflows, connecting to the user communities to capture the steps considered critical for analysis workflows
  • Task 2.4: Identify and fill gaps in the EDAM Ontology to enable cataloguing of biodiversity-relevant tools/services/workflows and other materials in Bio.tools, Galaxy, TeSS (WP4), WorkflowHub, and others (working closely with Tasks 2.1-2-3)
  • Example Case Study: ITSoneWB profiling global taxonomic diversity of eukaryotic communities on Galaxy, and the GlobalFungi Database analysis workflows

Milestones and deliverables

  • M2.1: Overview of main components of community-accepted biodiversity workflows
  • M2.2: A prioritisation list of workflows for inclusion in Galaxy and WorkflowHub
  • M2.3: EDAM concepts related to biodiversity research refined, updated, and added
  • D2.1: Bio.tools, WorkflowHub, and Galaxy subdomains, populated with tools and workflows for biodiversity research

WP3: Outreach, networking, and communications

Biodiversity is a very broad and diverse domain of research, in which many networks of infrastructures and initiatives are involved. The main aims of WP3 are to better describe the landscape of stakeholders ELIXIR is working with or needs to better engage with and to establish a “network of networks” for biodiversity research.

It will feed into WP1 and WP2 by identifying ongoing or planned work directly relevant for improving RDM practices, and by exposing tools, services, and analysis workflows that the wider community are developing. It will also help to link training and knowledge transfer activities of various projects and stakeholders to the ELIXIR Training Platform and WP4.

By leveraging ELIXIR’s federated structure, these network growing activities will support biodiversity research by improving connections between existing projects and communities, as well as by promoting synergies and aligning data and tools to the needs of researchers. This will also strengthen ELIXIR’s position as a partner in the planning and development of new projects and initiatives in the biodiversity data/research domain.

Lead

Henrik Lantz

Tasks

  • Task 3.1: Stakeholder and project (ongoing and planned) mapping exercise including a series of online questionnaires and idea gathering both within ELIXIR Nodes and externally in the form of funded local, national, regional, etc. projects and infrastructures or initiatives.
  • Task 3.2: Build the “network of networks” by reaching out to and connecting with: infrastructures or initiatives (e.g. DiSSCo, GBIF, Lifewatch-ERIC, Geo-BON, Planetary Biology at EMBL) operating both transnationally and nationally; Ongoing European Commission funded projects (e.g. BGE, BiCIKL, BIODT, BioDiversa+), Platforms (e.g. Data Platform) and relevant ELIXIR Communities (e.g. Galaxy, Metagenomics, and System Biology). This will provide the critical mass, as well as the lines of communication, that will be required to effectively run the efforts in the other WPs (such as the community-accepted workflows, relevant biodiversity terms, as well as data management aspects).
  • Task 3.3: Support meaningful interactions and exchanges through networking events, e.g. mini symposium at ELIXIR All Hands, online meetings for biodiversity-relevant projects to present themselves and discuss synergies, in-person meetings as satellites of other meetings, possibly also reaching out to connect with small and medium-sized enterprises working in the biodiversity domain.

Milestones and deliverables

  • D3.1: A prioritised list of international and national stakeholders and partners that will drive the “network of networks”
  • M3.1: Engagement and communication plan with priorities and actions
  • M3.2: Diverse networking events, with different focus, that bring stakeholders together
  • D3.2: An ELIXIR Biodiversity Community page, pointing to the collections of collated resources and further relevant pages/documents, highlighting the work of WP1, 2, and 4

WP4: Training and knowledge transfer

The overarching aim of WP4 is to leverage the strengths of ELIXIR’s training experience to help support the growth of the ELIXIR Biodiversity Community through network-driven sharing of training experiences and knowledge transfer and materials.

The work will be developed in close collaboration with the ELIXIR Training Platform and extensively use the methods already developed. Activities in Work Packages 1, 2, and 3 will help to connect to a wide range of relevant stakeholders and thereby feed WP4 with information about ongoing or planned training-related activities on the broader biodiversity community.

Lead

Patricia Palagi and Anne-Françoise Adam-Blondon

Tasks

  • Task 4.1: Based on the relevant communities and stakeholders, define the appropriate learning pathways that can be used to upskill researchers in the context of biodiversity studies, and by connecting this with WP2, also allow for the identification of potential gaps in tools, services and training, so that this can be prioritised by the relevant initiatives.
  • Task 4.2: Review, improve, and maintain a curated collection of biodiversity-relevant training resources (e.g. Galaxy for Ecology initiative), including materials (aiming for FAIR and open materials) and training and knowledge transfer events, published and made accessible through TeSS , GTN, etc.. and shared through the networks being mapped by activities in WP3.
  • Task 4.3: In collaboration with WP3 and the ELIXIR Training Platform, sustain and increase training capacity in the community by raising awareness and organising events to exchange knowledge and information in best practices, methods and datasets for training, on Train-the-Trainer (TtT) pedagogical training activities.

Milestones and deliverables

  • D4.1: Learning pathway(s), co-designed and co-created with the relevant communities
  • M4.1: A list of gaps and priorities for new training materials/topics to be developed
  • D4.2: A collection of training resources, as a TeSS Collection / GTN group links
  • D4.3: Project Mid-term reporting (for contractual purposes); to be provided by funded Nodes
  • D4.4: Scientific end report and Node-specific end report of the Implementation Study
ELIXIR France, ELIXIR Greece, ELIXIR Italy, ELIXIR Germany, ELIXIR Portugal, ELIXIR Ireland, ELIXIR Norway, ELIXIR Spain, ELIXIR UK, ELIXIR Switzerland, ELIXIR Hungary, ELIXIR Sweden, EMBL-EBI, ELIXIR Czech Republic

Over the coming decade, Europe will face critical challenges in maintaining biodiversity, ensuring food security and combating pathogens. Our 2024–28 Programme will address these issues by mobilising and integrating molecular data, using successful coordination models from human genomics. Through strategic investments and collaboration in externally-funded projects, ELIXIR will enhance scientific services and support transnational research in these essential areas.

The following projects have been selected as part of the ELIXIR 2024–28 Programme’s Biodiversity, food security and pathogens Science tier:

ELIXIR Belgium, ELIXIR France, ELIXIR Germany, ELIXIR Greece, ELIXIR Netherlands, ELIXIR Norway, ELIXIR Portugal, ELIXIR Slovenia, ELIXIR UK, EMBL-EBI, ELIXIR Italy

Cellular and molecular biology are fundamental to ELIXIR's mission. As part of our 2024–28 Programme, we are committed to advancing data services and software for research on nucleic acids, proteins and other biomolecules. This initiative will address new demands for multi-omics and multi-modal analyses, including imaging, by developing methods and partnerships. We will also expand expertise in reusable data and software to incorporate FAIR models, ensuring robust solutions for modelling at all scales. 

The following projects are key to connecting the latest developments with established data resources, unlocking the potential of cellular and molecular biology:

ELIXIR Belgium, ELIXIR Czech Republic, ELIXIR France, ELIXIR Greece, ELIXIR Hungary, ELIXIR Italy, ELIXIR Netherlands, ELIXIR Portugal, ELIXIR Slovenia, ELIXIR Spain, ELIXIR Sweden, ELIXIR UK, EMBL-EBI

This project aims to strengthen the basis for a one-stop shop connecting databases, datasets and tools for the deployment of the engineering Design-Build-Test-Learn (DBTL) framework in biotechnology. It will do so by surveying the tools and data landscape, pinpointing gaps and opportunities, and establishing design patterns for task-specific workflows for analysis, integration and sharing of multimodal data. 

It will provide a resource that will allow users to navigate the complex landscape of biotechnology tooling and data, as well as to establish solutions that fit their specific DBTL requirements. Use cases from ongoing programmes in various communities will be used to ascertain and establish the pragmatic value of the solutions. 

The work will be carried out through hands-on activities, dedicated workshops and hackathons, providing training and resources, as well as fostering industrial engagement. The experience of the communities and platforms involved in systems biology, industrial biotechnology, metabolic modelling, metabolomics, enzymes, bioprospecting and data management will be particularly valuable in this respect, as well as their respective industrial relations. Accordingly, the project engages participants from seven ELIXIR nodes and connects researchers and their activities from six communities. 

The project outcomes will contribute to advancing the ambition of connecting the latest developments and established data resources across ELIXIR to realise the potential of cellular and molecular biology, particularly in the fields of industrial biotechnology and biomanufacturing.

ELIXIR Spain, ELIXIR Greece, ELIXIR France, ELIXIR Netherlands, ELIXIR Portugal, ELIXIR Slovenia, ELIXIR UK

Project objectives

Understanding molecular biodiversity is essential for ecological conservation and sustainable development. While a vast array of molecular data awaits exploration, its lack of connectivity with other sources of data and metadata such as geographical reference, habitat, population size and phenotypic data often pose significant barriers to biodiversity research.

This project proposal is about developing Odyssey, a web portal in the form of a user-friendly interface that will allow researchers, educators and citizens to navigate the world of molecular biodiversity using Greece and Norway as case studies – two countries with a characteristic and unique wealth of biodiversity, representative for Mediterranean and Nordic types of ecosystems respectively. 

Based on existing sources of information and prototype applications available for specific regions and taxa, this project aims to link actual efforts and develop a new interface to offer diverse functionalities for data exploration and analysis, such as descriptive statistics, graphs, maps, customisable data filters and dynamic visualisations. Through modular design, the application will ensure flexibility and scalability, enabling easy integration of new data sets and analytical tools in the future. This approach will be used for training and communication, inviting traditional biodiversity research groups to utilise new information concerning the spatial patterns of biodiversity and their connection with features that are important for designing conservation measures, such as habitat connectivity, representativity, population demographics, dynamics of adaptation and migration.

Odyssey’s outcome will be a valuable tool for studying and, ultimately, offering a basis for managing and conserving the rich molecular biodiversity of Greece and Norway, as well as supporting the activities of the ELIXIR Biodiversity Community in the two Nodes and in Europe. This will promote collaboration, innovation and knowledge exchange in biodiversity research and beyond. 

This new tool will be developed and offered under an open-source licence, encouraging community participation and contribution to further enhance its capabilities and broaden its applications, fostering a robust network for biodiversity research in Greece and Norway.

Project outcomes

Odyssey: An Interactive R Shiny App to Explore Molecular Biodiversity in Greece
Presented at the 23rd European Conference on Computational Biology (ECCB2024) in Turku, Finland, Odyssey is an innovative R Shiny app designed to visualise and investigate molecular biodiversity across Greece. It provides an intuitive, user-friendly interface for exploring complex biological data through interactive visualisations.

Highlighted outcome (in progress)
Developed as an R package, The Odyssey app is being structured as a reusable R package to enable wider adoption and future scalability. Explore the code on GitHub. This outcome demonstrates the practical impact of ELIXIR’s support for open-source tools in biodiversity informatics.

Co-leads

  • Aristotelis C. Papageorgiou, Democritus University of Thrace, Greece
  • Helle Tessand Baalsrud, Norwegian University of Life Sciences, Norway
ELIXIR Greece, ELIXIR Norway

Project objectives

Understanding molecular biodiversity is essential for ecological conservation and sustainable development. While a vast array of molecular data awaits exploration, its lack of connectivity with other sources of data and metadata such as geographical reference, habitat, population size and phenotypic data often pose significant barriers to biodiversity research.

This project proposal is about developing Odyssey, a web portal in the form of a user-friendly interface that will allow researchers, educators and citizens to navigate the world of molecular biodiversity using Greece and Norway as case studies – two countries with a characteristic and unique wealth of biodiversity, representative for Mediterranean and Nordic types of ecosystems respectively. 

Based on existing sources of information and prototype applications available for specific regions and taxa, this project aims to link actual efforts and develop a new interface to offer diverse functionalities for data exploration and analysis, such as descriptive statistics, graphs, maps, customisable data filters and dynamic visualisations. Through modular design, the application will ensure flexibility and scalability, enabling easy integration of new data sets and analytical tools in the future. This approach will be used for training and communication, inviting traditional biodiversity research groups to utilise new information concerning the spatial patterns of biodiversity and their connection with features that are important for designing conservation measures, such as habitat connectivity, representativity, population demographics, dynamics of adaptation and migration.

Odyssey’s outcome will be a valuable tool for studying and, ultimately, offering a basis for managing and conserving the rich molecular biodiversity of Greece and Norway, as well as supporting the activities of the ELIXIR Biodiversity Community in the two Nodes and in Europe. This will promote collaboration, innovation and knowledge exchange in biodiversity research and beyond. 

This new tool will be developed and offered under an open-source licence, encouraging community participation and contribution to further enhance its capabilities and broaden its applications, fostering a robust network for biodiversity research in Greece and Norway.

Project outcomes

Odyssey: An Interactive R Shiny App to Explore Molecular Biodiversity in Greece
Presented at the 23rd European Conference on Computational Biology (ECCB2024) in Turku, Finland, Odyssey is an innovative R Shiny app designed to visualise and investigate molecular biodiversity across Greece. It provides an intuitive, user-friendly interface for exploring complex biological data through interactive visualisations.

Highlighted outcome (in progress)
Developed as an R package, The Odyssey app is being structured as a reusable R package to enable wider adoption and future scalability. Explore the code on GitHub. This outcome demonstrates the practical impact of ELIXIR’s support for open-source tools in biodiversity informatics.

Co-leads

  • Aristotelis C. Papageorgiou, Democritus University of Thrace, Greece
  • Helle Tessand Baalsrud, Norwegian University of Life Sciences, Norway
ELIXIR Greece, ELIXIR Norway