ELIXIR Switzerland

The SIB Swiss Institute of Bioinformatics is an internationally recognized non-profit organization, dedicated to biological and biomedical data science. 

Its data scientists are passionate about creating knowledge and solving complex questions in many fields, from biodiversity and evolution to medicine. They provide essential databases and software platforms as well as bioinformatics expertise and services to academic, clinical, and industry groups. SIB federates the Swiss bioinformatics community of about 900 scientists, encouraging collaboration and knowledge sharing.

The institute contributes to keeping Switzerland at the forefront of innovation by fostering progress in biological research and enhancing health.

SIB in figures (as of January 2023):

• 87 research and service groups
• 900 members, including 190 employees
• 28 institutional partners across Switzerland
• 160 databases and software tools developed by SIB members accessible via the Expasy web portal
• 100 course-days per year, making up over 60 courses provided to 1,400 participants
• Over 500 peer-reviewed articles published

SIB at ELIXIR

SIB is one of the largest national nodes within the ELIXIR consortium. As a provider of various renowned bioinformatics resources, expertise and teaching activities to the international life science community, SIB interacts with ELIXIR at several levels:

Open bioinformatics resources

• Over 160 tools and databases are developed by the SIB community and openly available on Expasy, the Swiss Bioinformatics Resource Portal. Among them, 14 are designated as SIB Resources. They are made up of 37 software tools and databases. Read more here.
• Five of the SIB Resources are part of ELIXIR Core Data Resources (Cellosaurus, Rhea, STRING, SWISS-MODEL, and UniProt), one of the ELIXIR Deposition Databases (ModelArchive), one of the ELIXIR Recommended Interoperability Resources (Bgee SPARQL endpoint), and five of the Global Core Biodata Resources (Bgee, Cellosaurus, Rhea, STRING, and UniProt).  Learn more about the recognition for SIB Resources on the worldwide stage here.

Participation in ELIXIR

• SIB co-leads the ELIXIR Data Platform, and the communities: 3D-BioInfo community, Food and Nutrition and Human Copy Number Variation. It is also involved in several other focus groups and workstreams, such as the benchmarking of software tools.
• Co-leading the training work package of the implementation study of the new ELIXIR Single-Cell Community.
• It is co-leading two work packages as part of the ELIXIR-CONVERGE project, whose aim is to help standardize life science data management across Europe: one around training and capacity building and one around SARS-CoV-2 genomic data sharing.
• SIB contributed to the development of the ELIXIR RDMkit, which is an online guide containing good data management practices applicable to research projects throughout the data lifecycle, as well as the FAIR Cookbook to bring these practices into reality.
• Involved in the ELIXIR-EXCELERATE project, to establish a pan-European data infrastructure for biological information.

Network

• SIB acts as Data Coordination Centre in numerous international public-private partnerships as part of the Innovative Health Initiative (IHI, previously IMI), harmonizing data and implementing FAIR principles across projects tackling cancer, diabetes and obesity.
• SIB has successfully established the BioMedIT network and the Swiss Personalized Health Network (SPHN) as FAIR, sustainable national infrastructure enabling responsible sharing of health data for research purposes.

Impact

• Launched a webpage showing how the life science infrastructure and data science expertise at SIB contribute to a better world and a stronger Switzerland: impact.sib.swiss.
• A study by SIB and supported by ELIXIR compared existing funding models towards sustainable funding of core data resources in the life sciences (Gabella C et al. F1000Research 2017, 6(ELIXIR):2051 - read more and watch the interview).
• SIB co-led the development of the governance and processes supporting the identification and evaluation of ELIXIR Core Data Resources (Durinx C et al., F1000Research 2016, 5:2422).

SIB events

SIB runs an extensive range of scientific events, including its main computational biology conference [BC]2 occurring every two years in Basel. More on the training events in the Events section.