Nextflow pipeline for splicing quantitative trait loci (sQTL) mapping based on sQTLseekeR2, performing the following analysis steps:
- Index the genotype file
- Preprocess the transcript expression data
- Test for association between splicing ratios (a multivariate phenotype) and genetic variants in cis (nominal pass)
- Obtain an empirical P-value for each phenotype (permutation pass, optional)
- Control for multiple testing.
Main website for the service
ELIXIR Node
bio.tools link