Weekly Brief, 7 October 2024

This week's highlights

Expansion of ELIXIR management training programme


The ELIXIR Training in Management (ELITMa) programme is expanding as part of the Horizon Europe-funded ELIXIR-STEERS project and the PeoplePulse internal ELIXIR project.

Read the news

A refresh of the ELIXIR Collaborations webpage


ELIXIR Hub has refreshed the ELIXIR Collaborations webpage as part of the ongoing efforts to strengthen ELIXIR's international presence.

Explore the new ELIXIR international collaborations and European RIs collaborations page

New vacancies at ELIXIR Hub


Manager ELIXIR Project Management Office

Help ELIXIR Hub drive the professional project management practices that underpin the implementation of ELIXIR's scientific programme and enable the effective management of our internal and external portfolio of projects.

Senior Project Manager (EC Projects)

Provide project management capacity for implementing ELIXIRs flagship European Commission project, the European Genomic Data Infrastructure project.

Recommended reads

A novel strategy for Glioblastoma treatment by natural bioactive molecules showed a highly effective anti-cancer potential

ELIXIR Italy paper


Glioblastoma is a severe form of brain tumor that has a high fatality rate. It grows aggressively and most of the time results in resistance to traditional treatments like chemo- and radiotherapy and surgery. In this article, the use of some natural compounds, such as Allium lusitanicum, Succisa pratensis, and Dianthus superbus, was explored to tackle Glioblastoma; they showed their impact on cell number reduction, which was partially given by cell cycle quiescence. Metabolic studies showed an induced cell oxidative stress modulation and a massive metabolic rearrangement.


Read more

Region-specific gene expression profiling of early mouse mandible uncovered SATB2 as a key molecule for teeth patterning

ELIXIR Czech Republic paper


This research performed a comprehensive analysis of gene expression at the early stages of odontogenesis to obtain complete knowledge of the signalling pathways involved in early jaw patterning. Gene expression was analysed separately on anterior and posterior areas of the lower jaw at two early stages of odontogenesis. Gene expression profiling revealed distinct region-specific expression patterns in mouse mandibles and the researchers also identified several new molecules exhibiting significant differences in expression along the anterior-posterior axis, which potentially can play a role during incisor and molar specification.

Read more

Updates from Nodes

New drug targets from RNA-binding proteins

Molecular dynamics simulations provide insights into how biomolecules interact with each other at the atomic level, which will provide new information for drug design.

Read the use case article

NIH funding to develop a global Pathogen Data Network


Led by SIB in partnership with EMBL-EBI and numerous other global partners, this network aims to provide infrastructure, tools, training, outreach and support to FAIR infectious-diseases data sharing and reuse. It will cover diverse biodata types, including host and pathogen genomics, transcriptomics, proteins, pathways and networks, imaging and cohorts.

Read the news from SIB
Read the news from EMBL-EBI

Updates from Communities

Single-Cell Omics Community training course Spatial omics data analysis

21 - 24 January 2025 | Lausanne, Switzerland
Registration deadline: 11 November 2024


This course will delve into the cutting-edge field of Spatial Omics, focusing on Spatially-Resolved Transcriptomics technology which provides unprecedented insights into the spatial organization of gene expression within tissues.

More information and registration

Updates from other initiatives

An introduction to High Performance Computing

4 - 5 December 2024 | Online
Registration deadline: 15 November 204

BioNTs third training workshop "An introduction to High Performance Computing" is built upon the Carpentries and HPC Carpentry online learning materials and will cover all basic concepts needed to access an HPC cluster and to run applications and workflows.

More information and registration

A new service for publishing sensitive medical research data deployed in a pilot project


The FEGA service, developed for sensitive biomedical research data, enables the secure publication of research data. The Federated European Genome-phenome Archive (FEGA) differs from other available publication and analysis services in that the data are not exported from the service, but analysed within a protected internal cloud service. FEGA is part of CSCs sensitive data services, which enable the use of sensitive data for research.

Read the news

Upcoming ELIXIR events & webinars

ELIXIR Training Courses & Webinars

The ELIXIR TeSS portal has a variety of interesting events and courses organised by the ELIXIR Nodes. For more, visit TeSS portal


SYBEL 2023 webinar (Systems Biology)
14 October 2024 | 15:00 - 16:00 CEST | Online

ELIXIR Estonia: Basic LINUX/Unix workshop
23 October 2024 | Tartu, Estonia


ELIXIR Estonia: Laboratory documentation with Markdown
30 October 2024 | Tartu, Estonia

ELIXIR Estonia: Version control with Git
6 November 2024 | Tartu, Estonia

de.NBI: How to efficiently access the data of BacDive, BRENDA, LPSN, SILVA and more
11 November 2024 | 14:00 - 16:00 CET | Online

SIB course: Data analysis and representation in Python
11 November 2024 | Online

SIB course: Interactive visualization with Python
12 November 2024 | Online

SIB course: NGS - Quality control, alignment, visualisation
20 - 22 November 2024 | Bern, Switzerland

ELIXIR Events and Conferences

BioHackathon Europe 2024
4 - 8 November 2024 | Barcelona, Spain

ELIXIR Federated Human Data Community day
19 November 2024 | Lisbon, Portugal

ELIXIR Interoperability Platform F2F meeting (hybrid) 2024
25 - 26 November 2024 | Hybrid - Manchester, UK

 

Job vacancies

All vacancies are also published on the ELIXIR website (also including those from industry). If you need our help communicating your new open positions, you can submit a job advertisement and it will automatically appear on our newsletters. Go to our vacancy page to submit a job

PhD Evolutionary Engineering of Synthetic Microbial Communities

Wageningen University

Senior Project Manager (European Commission Projects)

ELIXIR

ELIXIR Project Management Office Manager

ELIXIR

Scientific Project Officer

EMBL-EBI

Postdoctoral Fellow - EAZPOD 2024

EMBL-EBI