Web application for fast 3D structure visualisation with residue conservation

The collaboration between EMBL-EBI and ELIXIR Czech Republic enabled the development and release of a reusable, web based tool for linking sequence conservation information with biomolecular structural data.

As part of the project, the team at the ELIXIR Czech Republic (Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, IOCB) pooled their expertise in linking sequence data with structure stability, interactions and functions with EMBL-EBI’s experience in providing sequence similarity search (HMMER service).

The project allowed David Jakubec from IOCB to spend three months at EMBL-EBI working on the development of the 3DPatch web application, complemented by a suite of 3DPatch tools to extend the current functionality of EMBL-EBI resources PDBe, lnterPro and Pfam. The results were presented in a research paper published in the journal Bioinformatics (see below) and at the XV Discussions in Structural Molecular Biology conference in Nave Hrady, Czech Republic. 



18 September 2017 to 28 February 2018

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